Description:
This talk will address in detail the genomic pathways behind the sex hormone cascade in men and women, highlighting how genomic variations manifest into the uniqueness of the individual. The talk will also address potential interventive strategies for optimal hormonal health.
Learning Objectives:
- Review the metabolic pathways required for steroidogenesis in males and females
- Review the genomics that facilitate these pathways
- Review the genomic variations that can alter the efficiency of the steroidogenic pathways
- Evaluate possible interventive and therapeutic options for optimized hormone health – individualized based on the genomic profile
Dr. Mohammed is the Founder and President of ManaGeneDx, a leading and innovative provider of comprehensive Lifestyle Genomics and Personalized Medicine consulting. He is widely regarded as a pioneer in medical genomics and has been the recipient of multiple academic and industry awards.
Together with Dr. Steve Scherer (Director of the Toronto Center or Genomics at SickKids, Toronto), he founded, and acted as the interim CEO of YouNique Genomics, Canada’s first personalized and lifestyle genomics institute. He is the holder of several patents in the general fields of molecular diagnostics and genomics research, and is one of the most sought-after national and international conference speakers in the genre of personalized medicine.
While completing his clinical post-doctoral internship at the University of California, Los Angeles (UCLA), Dr. Mohammed was credited with discovering one of two genomic pathways that define drug resistance to the Novartis-developed leukemia therapy, Gleevec, and co-published these findings in the journal Science (2001) with the renowned oncologist Dr. Charles Sawyers. That same year, he was the co-author of the American Society of Human Genetics’ Paper of the Year Award with his mentor, Dr. Eric Vilain, for their discovery of the role of the Wnt4 gene in sex-reversal. These early studies helped to define Dr. Mohammed as one of the few genomic specialists with core competencies in both the genomic characteristics of childhood development, as well as the genomic etiology of oncology/cancer.
Most recently, through ManaGeneDx, Dr. Mohammed has been at the forefront of introducing personalized medicine and lifestyle genomics to concierge and executive medical clinics across the globe. Dr. Mohammed has served on the Canadian Board of Autistic Research and is a consultant to the world-renowned Toronto Center of Applied Genomics. He has had the honor of being the personal guest of the former Premiere of Ontario, the Honorable Dalton McGuinty, and on several occasions, the guest of the Canadian Consulate of California. He has also sat on several think tank panels, including ones from the FDA and National Institute of Health (NIH) and is a frequent academic lecturer on the role of genomics in medicine.
Lorna Vanderhaeghe is a women’s health advocate and author of 13 books including "A Smart Woman’s Guide to Hormones". She has been researching and writing on nutritional medicine for over 35 years. Early in her career she had the honor of working for the Journal of Orthomolecular Medicine alongside nutrition pioneers including the late Dr. Abram Hoffer the discoverer of vitamin B3. She was listed as one of Canada’s Top 100 Female Entrepreneurs in 2011, 2012 and 2013. With degrees in nutrition and biochemistry Lorna developed a line of nutritional supplements specifically for women. Lorna continues her mission of empowering women to achieve optimal wellness through nutrition and lifestyle changes.